Densitometric measurement of bone mass is used
to diagnose osteoporosis in postmenopausal women
and to guide treatment decisions. BMD measurements
are used to determine fracture risk and to assess
changes in bone mass over time in both treated
and untreated patients.3 The
NOF, U.S. Preventive Services Task Force (USPSTF),
and the International Society for Clinical Densitometry
(ISCD) recommend that all Caucasian women aged
> 65 years be offered BMD screening.
BMD is expressed as a T-score which is the number
of standard deviations
above or below the mean for a young adult healthy
population. Dual x-ray absorptiometry (DXA) of
the hip is the gold standard for the diagnosis
of osteoporosis using the WHO criteria. Central
measurements of BMD with DXA are used to determine
baseline BMD for follow-up measurements. The
readily available technologies available to measure
BMD include DXA, which is the most often used,
ultrasonography, QCT, and radiographic absorptiometry.
DXA can also be used to detect vertebral fractures
in patient undergoing BMD assessment. Whenever
possible, measurement of BMD at the spine and
hip is recommended in all patients.
|